Cislaghi Dott.ssa Francesca

Pubblicazioni su PubMed

• Fulminant Lymphocytic Myocarditis During Pregnancy Treated With Temporary Mechanical Circulatory Supports and Aggressive Immunosuppression.
  Circ Heart Fail

  2022 Dec;15(12):e009810. doi: 10.1161/CIRCHEARTFAILURE.122.009810.
  
  Veronese Giacomo, Nonini Sandra, Cannata Aldo, Aresta Francesca, Olivieri Guido, Montrasio Elisa, De Caria Daniele, Perna Enrico, Calini Angelo, Bottiroli Maurizio, Cislaghi Francesca, Pedrazzini Giovanna, Baltaro Federica, Quattrocchi Giuseppina, Pedrotti Patrizia, Russo Claudio F, Garascia Andrea, Mondino Michele, Ammirati Enrico
  
  
  
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• Predictors of prolonged mechanical ventilation in a cohort of 5123 cardiac surgical patients.
  Eur J Anaesthesiol

  2009 May;26(5):396-403. doi: 10.1097/EJA.0b013e3283232c69.
  
  Cislaghi Francesca, Condemi Anna Maria, Corona Alberto
  
  Abstract
  
  BACKGROUND:
  Prolonged mechanical ventilation (PMV) after heart surgery is associated with increased patient morbidity and mortality.
  
  METHODS:
  In this prospective observational cohort study the aim was to assess PMV predictors and its impact on ICU, hospital length of stay and survival in cardiac surgical patients admitted to our eight-bed ICU from January 2000 to December 2006. All perioperative patient variables were put into an electronic database. Five thousand one hundred and twenty-three patients were divided into two cohorts: early extubation, undergoing a successful extubation for 12 h or less, and delayed extubation, needing a mechanical ventilation for more than 12 h.
  
  RESULTS:
  A logistic regression model identified the following as PMV predictors: age more than 65 years [odds ratio (OR), 1.296; 95% confidence interval (CI), 1.017-1.069; P = 0.016], chronic renal failure (OR, 1.571; 95% CI, 1.566-2.466; P = 0.011), chronic obstructive pulmonary disease (OR, 1.453; 95% CI, 1.695-2.454; P = 0.006), redo surgery (OR, 2.010; 95% CI, 1.389- 2.114; P = 0.001), emergency surgery (OR, 1.622; 95% CI, 1.515-2.494; P = 0.016), New York Heart Association/Canadian Cardiovascular Society class higher than 2 (OR, 1.491; 95% CI, 1.704-2.321; P = 0.001), left ventricular ejection fraction of 30% or less (OR, 2.125; 95% CI, 1.379-1.991; P = 0.000), red blood cell (OR, 5.430; 95% CI, 3.636-8.130; P = 0.000) and fresh frozen plasma transfusion units more than four (OR, 3.019; 95% CI, 1.808-5.050; P = 0.000) and cardiopulmonary bypass time more than 77 min (OR, 2.030; 95% CI, 1.248-2.174; P = 0.002). Early extubation group patients showed a higher probability of being discharged from ICU to cardiac surgical ward (log-rank = 1108.951; P = 0.000) and from cardiac to rehabilitation ward (log-rank = 598.005; P = 0.000) and higher hospital survival (log-rank = 53.215; P = 0.000).
  
  CONCLUSION:
  This review allowed us to assess predictors, helping us to identify 'a priori' patients more likely to undergo PMV.
  
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• Timely selection of adequate antifungal therapy for candidemia in the critically ill: don't let the yeast rise!
  Crit Care Med

  2008 Nov;36(11):3097-8. doi: 10.1097/CCM.0b013e31818b9375.
  
  Corona Alberto, Cislaghi Francesca, Singer Mervyn
  
  
  
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